Chicago Health Officials Warn of Deadly Meningococcal Outbreak After Two Deaths

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By Gloria Nosa

Public health officials in Chicago have confirmed seven cases of meningococcal disease, which can cause fatal meningitis or a rapid bloodstream infection. Two people have died (stock)

Public health officials in Chicago have issued an urgent alert after confirming seven cases of meningococcal disease, a severe bacterial infection that can attack the brain and bloodstream. Two people have already died in the current outbreak.

The Chicago Department of Public Health (CDPH) traced the patients’ contacts and administered preventive antibiotics, but the source of the outbreak, which began on January 15, remains unidentified. With seven cases reported so far, the city may soon exceed its typical annual count of 10–15 cases.

“Meningococcal disease can progress rapidly,” the CDPH said. “Symptoms often begin like a common illness — fever, chills, fatigue, nausea — but can worsen within hours.” Residents are urged to seek medical attention immediately if they experience these symptoms, especially when combined with a stiff neck, sensitivity to light, cold extremities, severe body aches, vomiting, diarrhea, or a dark purple rash.

The disease spreads through prolonged contact with infected saliva or respiratory secretions, such as kissing or sharing utensils. It most commonly affects teenagers, young adults, and the elderly. The MenACWY vaccine is recommended for children at ages 11–12, with a booster at 16, while the MenB vaccine is advised for 16–23-year-olds at higher risk.

Midwestern meningococcal disease outbreak: 7 cases, 2 deaths since mid-January | Fox News

How the infection progresses
After initial exposure, the bacteria may live harmlessly in the throat. Problems begin when the pathogens enter the bloodstream, multiply rapidly, and release toxins that trigger a severe systemic reaction. Within hours, patients can experience septic shock, organ failure, and a distinctive dark red or purple rash.

If the bacteria reach the nervous system, meningitis can develop, causing confusion, stiff neck, and sensitivity to light. The entire process — from first symptoms to life-threatening collapse — can occur in less than 24 hours, making immediate medical intervention critical.

Dr. Marielle Fricchione, a pediatric infectious disease expert, told ABC News: “Even losing a half hour can allow the bacteria to spread to the blood and brain. To see a cluster with two deaths already is very concerning.”

The outbreak comes amid a nationwide resurgence of meningococcal disease. Preliminary CDC data show 503 confirmed and probable cases in 2024, the highest annual total since 2013. Serogroup Y, once rare, has become a leading cause of recent U.S. outbreaks.

A recent CDC update narrowed childhood meningococcal vaccine recommendations to high-risk groups, leaving the decision for other adolescents to families and doctors. Experts warn that reduced vaccination coverage can allow outbreaks like the one in Chicago to spread rapidly.

Dr. Fricchione added, “This is exactly the scenario you worry about — an outbreak can escalate quickly if teenagers and college students aren’t vaccinated.”

Meningitis cases rise in major Midwestern city, prompting public health alert

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