Turning off anxiety
Anxiety: the most common mental health problem
Low efficacy of anti-anxiety drugs
How anxiety changes our brains
Alterations in the amygdalae
Amygdalae: responsible of processing threats
The amygdgalae, a pair of small almond-shaped regions deep in the brain (pictured in blue), is best known as the part of the brain that drives the so-called “fight or flight” response to threats, thus associated with anxiety disorders.
Anxiety experiment in mice
Increase of small molecules
A molecule that produces an anxiolytic effect
A molecular break
This means that miR-483-5p acts as a molecular brake that offsets stress-induced amygdala changes to promote anxiety relief.
Towards new anxiety treatments
The discovery of how this molecule regulates our response to stress in the brain may be the first stepping stone towards the creation of much-needed treatments for anxiety disorders, researchers said.